Indapamide
NHS information about the medicine indapamide, including what it’s used for, who can take it, how to take it and side effects.
What indapamide is for
Indapamide is a type of medicine called a diuretic.
Diuretics are sometimes called water tablets because they make you pee more.
In people with high blood pressure (hypertension), indapamide can lower blood pressure and help reduce the risk of serious conditions such as heart attacks and stroke.
How to take indapamide
Indapamide comes as a tablet you swallow. You usually take it once a day.
Your doctor will tell you how much to take and for how long. Indapamide treatment for high blood pressure is often long term.
When taking indapamide:
- take it in the morning
- swallow the tablet whole with some water
Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.
You may need regular blood tests to check the medicine is not affecting your potassium levels.
If you get ill with vomiting, diarrhoea or a high temperature (fever) when taking indapamide, there's a risk you'll get dehydrated.
Talk to a pharmacist or doctor for advice or follow the advice they've already given you.
If you miss a dose of indapamide
If you forget to take a dose of indapamide, take it as soon as you remember, unless it's nearly time for your next dose.
If it's nearly time for your next dose, skip the dose you missed and take your next dose the next day as usual.
Do not take 2 doses to make up for a missed dose.
If you take too much indapamide
Taking an extra dose of indapamide is unlikely to cause problems, but it's important to get medical advice if you take too much because it can sometimes be dangerous.
Side effects of indapamide
Like all medicines, indapamide can cause side effects, although not everyone gets them.
Some side effects should ease after a while as your body gets used to the medicine, but others can last longer.
Common side effects
Common side effects of indapamide include:
- a bumpy, red rash – this may be more difficult to see on brown or black skin
- headaches
- low blood pressure (hypotension), which can make you feel dizzy, especially when standing up
- feeling sick (nausea)
Indapamide may make you pee more often when you first start taking it, but your peeing should return to normal after a few weeks.
These are not all the side effects of indapamide.
For a full list, see the leaflet inside your medicines packet, or search for your medicine leaflet on the electronic medicines compendium website.
You can report any side effects you get on the Yellow Card Scheme website
Who can and cannot take indapamide
Most adults can take indapamide. It is not recommended for children.
Indapamide is not suitable for some people. For example, it may not be suitable if:
- you’ve had an allergic reaction or serious side effect from indapamide or a similar medicine before
- you have diabetes
- you have kidney or liver disease
- you have gout
- you have a heart rhythm problem
- you have Addison's disease
- you’ve been told you have low blood potassium or salt levels, or high calcium levels
Before taking indapamide, tell your doctor or a pharmacist if you have any medical conditions.
Breastfeeding and indapamide
Tell your doctor if you're breastfeeding.
Indapamide is not usually used if you're breastfeeding as small amounts may pass into breast milk.
Pregnancy and indapamide
Tell your doctor if you're pregnant or you get pregnant while taking indapamide.
Indapamide is not usually recommended for use in pregnancy.
Taking indapamide with other medicines, food and drink
There are some medicines, remedies and supplements that may not mix well with indapamide.
These include:
- non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen
- calcium supplements
- lithium, used to treat mood disorders such as bipolar disorder
- tricyclic antidepressants (TCAs), such as amitriptyline and nortriptyline
- allopurinol, used to treat gout
- some medicines used to treat heart rhythm problems
- other blood pressure medicines
Before taking indapamide, tell your doctor if you're taking any other medicines, herbal remedies, vitamins or supplements.
Food and alcohol with indapamide
You can eat as normal while taking indapamide, but it may be best to avoid drinking alcohol because it can increase the risk of low blood pressure (hypotension).
To find out more about your medicine, you can:
- check the leaflet that comes with it
- search for your medicine leaflet on the electronic medicines compendium website
- speak to a pharmacist or doctor for advice – if you recently started taking it, you can get help with newly prescribed medicines from a pharmacist as part of the New Medicine Service
